For a while I have been playing Mass Effect 1 & 2 with Xbox. Earlier I tried to play Oblivion and now I bought Dragon Age: Origin. All of those should be great games.
Most of rpg:s are placed in fantasy worlds like good ol' Dungeons & Dragons. For pc there were not too much good scifi rpg:s. Some old farts would mention Sentinel Worlds. And then was Fallout 1 & 2 but at that time I did not play much.
And now I was playing those four games and liked much more Mass Effects. Even there is lots of fantasy rpg:s they all look quote same. I always end up carrying 20 pieces of leather pants because they are worth of coin or two. And at the end of the game I have so much potions I could put up an drugstore. I never use most of them because I could need them later in the game. And when the final battle comes I'm too busy to use them all.
Other thing I hate especially in Oblivion and Dragon Age is collecting flowers. I should be a hero, not a florist. Fantasy games usually have some kind of a alchemy system but I am too lazy to learn them. Flowers could be used in potions but always some guy wants me to pick up flowers for him.
Scifi games are usually simplier. You don't need to collect million kinds of different junk just because you may need it or you don't know is it valuable or not. In fantasy games I always have to throw away three pairs of sandals and that valuable drarwen hammer because I cannot move any more. It also seems that in Mass Effects (and Fallouts?) you can make more decissions and what you do and say has more effect to the world.
Or maybe I've just played wrong games but fantasy games seem to be quite same kind. Only fantasy games I love to play these days are Eschalon series. But it is isometric and turn based so there is more time to think. And no flower collecting.
Maybe I just should start playing Fallout 3 wich I bought almost a year ago. I have plenty of a time before Mass Effect 3 arrives next year. I just pre-ordered its Collectors Edition. I like those artbooks.